Centre for Translational Chemical Biology - CTCB



The Centre for Translational and Chemical Biology (CTCB) provides facilities and expertise to promote interdisciplinary research across biology, chemistry and medicine.

The CTCB is a network of over 60 independent research labs with centralised protein production and characterisation facilities through the Edinburgh Protein Production Facility (EPPF). There is also expertise in Structural Biology, Virtual Screening and Structure Based Design.

It facilitates:

Protein production and characterisation.

Virtual screening for drug leads.

Commercial opportunities.

Practical training.


Prof. Malcolm Walkinshaw
Rm. Swann 3.21
Tel (+44) 0131 6507056
Fax (+44) 0131 6507055
email: malcolm.walkinshaw@ed.ac.uk

Prof. Paul Barlow
Rm. Swann 3.21
Tel (+44) 0131 6504727
Fax (+44) 0131 6507155
email: Paul.Barlow@ed.ac.uk

Facilities Manager:
Dr. Martin Wear
Rm. Swann 3.20
Tel (+44) 0131 6507054
Fax (+44) 0131 6507055
email: martin.wear@ed.ac.uk


Protein Production
Biophysical Characterisation
In Silico Screening


On-line Booking
Core Column Library

Science Conversations - making good 

Access Charges/Costs:

Access Charges/Costsmailto:m.walkinshaw@ed.ac.ukmailto:Paul.Barlow@ed.ac.uk?subject=mailto:m.wear@ed.ac.ukEPPF_-_Protein_Production.htmlEPPF_-_Biophysical_characterisation.htmlIn_Silico_tools.htmlhttp://www.chem.ed.ac.uk/research/services.htmlhttp://www.bionmr.chem.ed.ac.uk/bionmr/index.htmlhttp://cryo-em.bio.ed.ac.ukTraining.htmlhttp://booked.bch.ed.ac.uk/booked/Web/index.php?redirect=Core_Column_Library.htmlScience_Conversations_-_making_good.htmlScience_Conversations_-_making_good.htmlAccess_charges_costs.htmlEPPF_-_Protein_Production.htmlshapeimage_3_link_0shapeimage_3_link_1shapeimage_3_link_2shapeimage_3_link_3shapeimage_3_link_4shapeimage_3_link_5shapeimage_3_link_6shapeimage_3_link_7shapeimage_3_link_8shapeimage_3_link_9shapeimage_3_link_10shapeimage_3_link_11shapeimage_3_link_12shapeimage_3_link_13shapeimage_3_link_14


University of Edinburgh,

Michael Swann Building, L3

King’s Buildings,

Mayfield Rd.,

EH9 3JR,



Centre for Translational and Chemical Biology - CTCB

Upcoming Events


AKTA Pure LC Training: 2 pm - 4 pm, in Swann 3.17






“Introduction to AKTA Pure LC equipment”

Dr. Matt Nowicki. 

The EPPF has a purification suite the consists of four ÄKTA Pure 25 systems, two ÄKTAXpress systems and an ÄKTAMicro HPLC. ÄKTA Pure 25 is a new generation, flexible and intuitive chromatography systems, running UNICORN 7.1 control software, designed for fast purification of proteins, peptides, and nucleic acids from microgram to gram levels.

Any researcher who is interested in learning how to use the LC systems and associated purification resources in the EPPF should consider attending. Researchers with no, or limited, previous knowledge of this technique are particularly encouraged to attend; more experienced users should contact EPPF staff to arrange a more bespoke training or to discuss particular needs/requirements. are also welcome.

There are 4 places available for each of the hands-on training session.

If you are interested, please contact matthew.nowicki@ed.ac.uk.